What are some of the well known tools for creating games for e-learning?
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Adobe Flash, Adobe Captivate, Articulate Storyline, Articulate Presenter, and yes, Powerpoint are the industry standards. eLearning Brothers has a bunch of e-learning game templates: http://elearningtemplates.com/el… in some of these commonly used formats.
You can also make simple 8-bit games using GameMaker http://www.yoyogames.com/gamemak…
You could also use Scratch, which requires little to no programming knowledge. Here some interesting examples of games created in Scratch: http://scratch.mit.edu/galleries…
Note though that for GameMaker and Scratch it may be a little tricky natively packaging them in SCORM compliant modules if you are looking to deploy them in a learning management system. Might have to link to them or embed them as web objects.